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ANZSCDB: Advertisement for career positions / scholarships

POSTDOC POSITIONS
The Department of Cell Biology at the Erasmus Medical Centre,
Rotterdam, The Netherlands


Cytoskeletal dynamics and intracellular transport


Cell Biology: Candidates with an interest in live-cell imaging and mechanisms of cell motility, protein trafficking, organelle transport and microtubule dynamics.

Biochemistry: Candidates with an interest in protein biochemistry including protein purification and proteomics-based techniques such as mass spectrometry.

Imaging and Biophysics: Candidates with backgrounds in physical science with an interest in developing and applying optical imaging techniques at the cellular level or for in vitro assays, and developing quantitative models.

Projects:

1. Spatial organization of cadherin junctions by dynamic microtubules: an integrated model.

The aim of the project is to investigate how microtubules control the formation and maintenance of the cadherin-based cell-cell adhesions using a set of tools for recently discovered novel microtubule plus end tracking proteins.

2. Mechanisms of bi-directional microtubule-based transport.

The aim of the project is to investigate how microtubule plus and minus end directed motors present on the same cargo are coordinated in time and space. As a model we use exocytotic vesicles bound to cytoplasmic dynein and several kinesins.

The projects include intense collaborations with laboratories in the USA, Great Britain, Switzerland and Australia.
Information and application

Dr. Anna Akhmanova
e-mail: a.akhmanova@erasmusmc.nl
phone:+31-10-7038134
http://www2.eur.nl/fgg/ch1/akhmanova/index.html


imbResearch Officer /
Senior Research Officer in Cell Biology

POSITION: A postdoctoral/senior postdoctoral position is available on a project that focuses on the trafficking and secretion of key inflammatory proteins in immune cells and epithelial cells, and in disease models. Applicants should possess a PhD in a relevant discipline (eg. cell biology/biochemistry/immunology) with several years experience in the field of protein trafficking. Expertise in microscopy and cell imaging is essential. Other expertise in a range of molecular and cell biology techniques is desirable, including immunostaining, handling of mammalian epithelial and immune cell lines, cell transfection, protein analysis and live cell imaging. The remuneration package will be in the range $47,792– $64,827 p.a. (Academic Level A) or $79,840 to $94,809 (Academic Level B), plus employer superannuation contributions of 17% (total package will be in the range $55,917 - $75,847 (Academic Level A) or $68,239 - $81,034 (Academic Level B) p.a.). This is a full-time, fixed term appointment for 3 years.

LABORATORY: The Institute for Molecular Bioscience is a national research and development initiative at the University of Queensland. The Institute incorporates the Centre for Molecular & Cellular Biology, the Centre for Drug Design and Development, and the ARC Special Research Centre for Functional and Applied Genomics.

ENQUIRIES:
Professor Jenny Stow, email
Human Resources - eMail


thisse
Postdoctoral positions available on zebrafish embryonic development
Thisse Laboratory, Department of Cell Biology,
The University of Virginia, USA

POSITION: 3-year postdoctoral positions are available in Christine and Bernard Thisse laboratory. Successful applicants will investigate the molecular control of the zebrafish early embryogenesis focusing on mechanisms responsible for patterning and early morphogenesis. The project is fully funded (salary, materiel and supplies) for the 3-year period. Requirements: Ph.D. (development, cell biology, molecular biology). Candidates should have expertise in developmental biology, cell biology or signaling.

PROJECT: New and ongoing areas of research interests include: Crosstalk between the Nodal, BMP, Wnt and FGF signaling pathways at the molecular and cellular levels.Role of these factors and of their target genes in early morphogenetic movements and cell division

CLOSE OF APPLICATION: The positions will remain open to applications until filled.

ENQUIRIES: Interested individuals should send their CV, a brief letter describing research experience and the names and contact information of two past advisors or mentors to christhisse@virginia.edu


UNIVERSITY OF OTAGO
Postdoctoral Fellowship
Department of Medical and Surgical Sciences
Section of Orthopaedic Surgery
Dunedin, New Zealand

PROJECT:
Skills in cell and tissue culture, molecular analysis and live cell imaging are required, and some familiarity with a dynamic cell-loading system would be an advantage. A strong understanding of cell biology and the role of primary cilia in mechanosensation will be essential. The appointee will be expected to develop cell culture techniques using the Flexercell cell straining system to examine the influence of mechanical strain on the proliferative, synthetic and calcium signalling capacity of normal ciliated and mutant non ciliated fibroblasts under mechanically strained and unstrained conditions. The individual appointed will be directly responsible to Associate Professor Tony Poole, Section of Orthopaedic Surgery, Department of Medical and Surgical Sciences, Dunedin School of Medicine.

POSITION:
A talented post-doctoral candidate with research experience in mechanobiology, including cell signalling pathways, connective tissue biology and real-time calcium imaging. The prime function of the research is use in vitro culture techniques to examine the influence of primary cilia expression on the biomechanical and physiological responsiveness of mutant and wild-type fibroblast cell lines.

The Marsden funded research to be completed over three years involves biomechanical and biochemical studies on the function of primary cilia in kidney cells.

CLOSING DATE: Open

ENQUIRIES:
Associate Professor C.A. (Tony) Poole,
Dunedin School of Medicine
Phone: 03 474 0999 ext 8613.
Email
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